Achieving Superior Process Control in Bioreactors and Fermentation Systems
Success in food and industrial bioprocessing relies on bioreactor and fermentation monitoring to optimize microbial growth, nutrient balance, and metabolite production. Real-time, aseptic sampling is essential to maintain sterility, ensure regulatory compliance, and maximize product consistency. Without reliable sampling, even minor process fluctuations can lead to contamination, inefficiency, and lost revenue.
The Role of Aseptic Sampling in Fermentation Process Control
Traditional bioreactor sampling is expensive, often unsafe, and increases the risk of contamination, inaccurate data, and operational inefficiencies. Aseptic bioreactor sampling with QualiTru aseptic sampling systems eliminates these risks by providing aseptic, contamination-free access for real-time monitoring.
Key benefits of aseptic sampling:
- Safeguard Against Contamination – Helps safeguard against contamination without the need for costly, complex, and unsafe steam sterilization.
- Real-Time Data Collection – Continuous monitoring of pH, dissolved gases, microbial viability, nutrient depletion, and microbial contamination.
- Process Optimization – Supports data-driven adjustments to maximize yield and maintain fermentation consistency.
Transforming Fermentation Research with QualiTru Sampling Systems
Aseptic sampling is critical for collecting comprehensive data and enabling more precise research. NORCE, a Norwegian research institute specializing in bioreactor and industrial fermentation research, faced significant limitations in data collection due to having only a single steam-sterilizable sampling valve per reactor. To address this challenge, NORCE integrated QualiTru’s aseptic sampling ports and pre-sterilized septa into their bioreactors. By installing these innovative solutions at three different locations within each bioreactor, they were able to monitor pH, microbiology, dissolved gases, and other crucial chemistry indicators throughout the fermentation process.
This approach significantly improved NORCE’s data collection capabilities, allowing them and their partners to adapt and optimize processes more effectively. With a deeper understanding of fluid dynamics and its impact on kinetics, NORCE achieved notable improvements in process yield. The QualiTru sampling system has empowered the NORCE team to collect precise and aseptic data, a key factor in the success of their research projects, particularly in upscaling various fermentation processes. By leveraging these advanced and user-friendly sampling systems, NORCE continues to innovate and achieve superior outcomes in fermentation research.
QualiTru’s Aseptic Sampling Solutions for Bioreactors
QualiTru’s aseptic sampling systems provide precision, ease of use, and quick reliability for bioreactor and fermentation monitoring:
- Pre-sterilized TruStream™ Septa – Sterile multi-use sampling with minimal labor and no downtime.
- TruStream7 Stainless Steel Ingold Ports – Designed for seamless integration into fermenters and bioreactors.
- Non-invasive, Multi-Point Sampling – Collects representative samples from different reactor zones for superior process visibility.
Optimize Your Bioprocess with Reliable Monitoring
Strengthen your process control with QualiTru’s validated aseptic sampling solutions engineered for precision and compliance. Contact us today to learn how our technology can enhance your bioreactor and fermentation monitoring processes.
Designed for bioreactor and fermentation monitoring, QualiTru’s aseptic sampling solutions provide a simple, fast, and versatile way to monitor bioreactor performance. Engineered for seamless integration, these pre-sterilized, ready-to-use systems enhance process control, microbial viability, and regulatory compliance.
- TruDraw Sterile Single Sampler (Part #112021)
- TruStream7 Ingold Port (Part 217105
- TruStream7 Tri-Clamp Port (Part #211125, 211129, 211133 & 211137)
- TruStream7 Septum – High Temp (Part #110021)
- TruStream12 Tri-Clamp Port (Part #211164, #211168 & #211174)
- TruStream12 Septum – High Temp (Part #110074)
